Recurrent acute kidney injury in preterm neonates is common and associated with worse outcomes and higher mortality
Autor: | Yamini Singh, Alok Bhutada, Juan C. Kupferman, Oluwatobi O Adegboyega, Shantanu Rastogi |
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Rok vydání: | 2021 |
Předmět: |
Pediatrics
medicine.medical_specialty Neonatal intensive care unit urologic and male genital diseases Infant Newborn Diseases chemistry.chemical_compound Risk Factors Intensive Care Units Neonatal medicine Humans Stage (cooking) Retrospective Studies Creatinine urogenital system business.industry Incidence (epidemiology) Infant Newborn Acute kidney injury Infant Gestational age Acute Kidney Injury medicine.disease female genital diseases and pregnancy complications Confidence interval chemistry Pediatrics Perinatology and Child Health business Kidney disease |
Zdroj: | Pediatric Research. 92:284-290 |
ISSN: | 1530-0447 0031-3998 |
DOI: | 10.1038/s41390-021-01740-y |
Popis: | BACKGROUND Acute kidney injury (AKI) in preterm neonates is associated with poor outcomes that may worsen in the setting of recurrent episodes of AKI. This study defines and studies the incidence, risk factors, and outcomes of recurrent AKI (rAKI). METHODS Retrospective chart review of the neonates born at a gestational age of ≤28 weeks admitted to the neonatal intensive care unit (NICU) between January 2014 and December 2018. We identified AKI based on the serum creatinine (Scr) concentrations using the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. rAKI was defined as the occurrence of AKI after Scr from the prior AKI had returned to baseline. RESULTS Forty-nine of the 205 (24%) preterm neonates developed rAKI. An earlier diagnosis ( |
Databáze: | OpenAIRE |
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