The obstetric outcome of singleton pregnancies following in-vitro fertilization/gamete intra-Fallopian transfer
| Autor: | Jim X. Wang, O. M. Petrucco, Christine Kirby, Gregory Philipson, Graham Anderson, A.M. Clark, Colin D. Matthews |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Infertility medicine.medical_specialty Pregnancy High-Risk medicine.medical_treatment education Population Fertilization in Vitro Pregnancy Odds Ratio medicine Humans Gamete intrafallopian transfer reproductive and urinary physiology Unexplained infertility Gynecology education.field_of_study business.industry Obstetrics Rehabilitation Infant Newborn Pregnancy Outcome Obstetrics and Gynecology Odds ratio Infant Low Birth Weight medicine.disease Gamete Intrafallopian Transfer female genital diseases and pregnancy complications Parity Low birth weight Reproductive Medicine Infant Small for Gestational Age Regression Analysis Small for gestational age Female medicine.symptom business Infant Premature Maternal Age |
| Zdroj: | Human Reproduction. 9:141-146 |
| ISSN: | 1460-2350 0268-1161 |
| DOI: | 10.1093/oxfordjournals.humrep.a138304 |
| Popis: | The present study compares 465 singleton live deliveries from in-vitro fertilization/gamete intra-Fallopian transfer (IVF/GIFT) pregnancies with a large control population to evaluate the incidence of pre-term delivery and small for gestational age (SGA) or very small for gestation age (VSGA) babies resulting from IVF/GIFT pregnancies. Overall the incidence of SGA or VSGA from an IVF/GIFT pregnancy is higher than from the normal obstetric population (SGA odds ratio 1.76, 95% confidence interval (CI): 1.38-2.25 and VSGA odds ratio 1.61, 95% CI: 1.05-2.46) particularly among primiparous women (SGA odds ratio 1.99, 95% CI: 1.25-3.16 and VSGA odds ratio 1.97, 95% CI: 1.49-2.62). After stratifying by the cause of infertility, only women with unexplained infertility had a significantly higher proportion of SGA/VSGA babies. There was a significantly higher incidence of pre-term deliveries among the young primiparae (odds ratio 5.02, 95% CI: 3.09-8.13). Thus the excess risk of delivering a SGA/VSGA baby and pre-term delivery from an IVF/GIFT pregnancy seems to be largely confined to women with unexplained infertility and young primiparae. |
| Databáze: | OpenAIRE |
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