Comorbidity and dementia: A nationwide survey in Taiwan
| Autor: | Shu Chien Yang, Pei Ning Wang, Ker Neng Lin, Li Yu Tang, Chung-Chih Lin, Yu Sun, Ming-Jang Chiu, Szu Yu Yiao, Huey Jane Lee, Ting Bin Chen, Ta-Fu Chen |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Pulmonology Epidemiology Cross-sectional study lcsh:Medicine Blood Pressure Comorbidity Logistic regression Vascular Medicine 0302 clinical medicine Endocrinology Medicine and Health Sciences Medicine 030212 general & internal medicine lcsh:Science Geriatrics Aged 80 and over Cognitive Impairment Multidisciplinary Cognitive Neurology Liver Diseases Neurology Cirrhosis Hypertension Regression Analysis Female Research Article medicine.medical_specialty Endocrine Disorders Cognitive Neuroscience Cerebrovascular Diseases Taiwan Gastroenterology and Hepatology 03 medical and health sciences Internal medicine Diabetes mellitus mental disorders Mental Health and Psychiatry Diabetes Mellitus Dementia Humans Asthma Aged business.industry lcsh:R Biology and Life Sciences medicine.disease Health Surveys Cross-Sectional Studies Metabolic Disorders Older people--Health and hygiene Physical therapy Cognitive Science lcsh:Q business 030217 neurology & neurosurgery Neuroscience |
| Zdroj: | PLoS ONE PLoS ONE, Vol 12, Iss 4, p e0175475 (2017) |
| ISSN: | 1932-6203 |
| Popis: | Background Comorbid medical diseases are highly prevalent in the geriatric population, imposing hardship on healthcare services for demented individuals. Dementia also complicates clinical care for other co-existing medical conditions. This study investigated the comorbidities associated with dementia in the elderly population aged 65 years and over in Taiwan. Methods We conducted a nationwide, population-based, cross-sectional survey; participants were selected by computerized random sampling from all 19 Taiwan counties between December 2011 and March 2013. After exclusion of incomplete or erroneous data, 8,456 subjects were enrolled. Of them, 6,183 were cognitively normal (control group), 1,576 had mild cognitive impairment (MCI), and 697 had dementia. We collected information about types of comorbidities (i.e., vascular risk factors, lung diseases, liver diseases, gastrointestinal diseases, and cancers), Charlson comorbidity index score, and demographic variables to compare subjects with normal cognition, MCI, and dementia. Results Regardless of the cognitive condition, over 60% of the individuals in each group had at least one comorbid disease. The proportion of subjects possessing at least three comorbidities was higher in those with cognitive impairment (MCI 20.9%, dementia 27.3%) than in control group (15%). Hypertension and diabetes mellitus were the most common comorbidities. The mean number of comorbidities and Charlson comorbidity index score were greater in MCI and dementia groups than in control group. Logistic regression demonstrated that the comorbidities significantly associated with MCI and dementia were cerebrovascular disease (OR 3.35, CI 2.62–4.28), cirrhosis (OR 3.29, CI 1.29–8.41), asthma (OR 1.56, CI 1.07–2.27), and diabetes mellitus (OR 1.24, CI 1.07–1.44). Conclusion Multiple medical comorbid diseases are common in older adults, especially in those with cognitive impairment. Cerebrovascular disease, cirrhosis, asthma, and diabetes mellitus are important contributors to cognitive deterioration in the elderly. Efforts to lower cumulative medical burden in the geriatric population may benefit cognitive function. |
| Databáze: | OpenAIRE |
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