A histopathologic study of oral mucosal lupus erythematosus
| Autor: | Tuomo K. Karjalainen, Charles E. Tomich |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Epithelium Pathology and Forensic Medicine Diagnosis Differential Atrophy Lupus Erythematosus Discoid Edema medicine Humans Lupus Erythematosus Systemic General Dentistry Aged Lamina propria Lupus erythematosus Hyperplasia business.industry Lichen Planus Mouth Mucosa Middle Aged medicine.disease Connective tissue disease medicine.anatomical_structure Vacuolization Connective Tissue Blood Vessels Histopathology Female medicine.symptom business Mouth Diseases |
| Zdroj: | Oral surgery, oral medicine, and oral pathology. 67(5) |
| ISSN: | 0030-4220 |
| Popis: | Specimens representing 17 cases of each of oral mucosal lupus erythematosus (LE) and lichen planus were examined under the light microscope to establish a set of histopathologic criteria that would distinguish between the two. Statistical analysis showed that significant differences in histopathology exist between the two diseases. A classic case of LE was found to exhibit the following characteristics: vacuolization of keratinocytes, patchy PAS-positive deposits subepithelially, edema in the lamina propria, PAS-positive thickening of blood vessel walls, and the presence of a severe or perivascular inflammatory cell infiltrate. A number of other less significant alterations were also identified. It is concluded from this study that oral LE in most cases is characteristic enough to provide a definitive diagnosis at the light microscopic level. |
| Databáze: | OpenAIRE |
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