Radiation Modalities Used in Lung Cancer: An Overview for Thoracic Surgeons
| Autor: | Puja Gaur Khaitan, Jonathan W. Lischalk, Pamela Randolph-Jackson, Mary McGunigal |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Lung Neoplasms medicine.medical_treatment Disease 030204 cardiovascular system & hematology Gray (unit) 03 medical and health sciences 0302 clinical medicine Proton Therapy Humans Medicine Medical physics Lung cancer Proton therapy Surgeons Modalities Modality (human–computer interaction) business.industry Interstitial lung disease General Medicine medicine.disease Radiation therapy Treatment Outcome 030228 respiratory system Surgery Immunotherapy Cardiology and Cardiovascular Medicine business |
| Zdroj: | Seminars in Thoracic and Cardiovascular Surgery. 33:1114-1121 |
| ISSN: | 1043-0679 |
| DOI: | 10.1053/j.semtcvs.2021.02.023 |
| Popis: | Radiation is a constantly evolving technology which plays a role in the management of lung cancer in a variety of settings: as an adjunct to surgery, definitively, and palliatively. Key aspects of radiation oncology-including acute and chronic toxicities of thoracic radiation and rationale for choosing one modality of radiation over another-may be obscure to those outside the field. We aim to provide a useful overview relevant for the thoracic surgeon of radiation technology and delivery. A review was performed of salient articles identifying radiation technologies used in lung cancer which were summarized and expounded upon with focus on integrating their history, evolution, and landmark trials establishing basis of their use. This article reviews the four fundamental means of external beam radiation employed in managing lung cancer and provides visual examples of comparison plans. We also touch on potential practice-changing developments in regards to proton therapy and radiation in the era of immunotherapy. Radiation oncology has evolved considerably over time to become a critical part of lung cancer management, particularly in early-stage inoperable disease and locally advanced disease. Maximizing tumor control while minimizing toxicity drives treatment strategies. Knowledge of these fundamentals will help the thoracic surgeon answer many questions patients pose regarding radiation. |
| Databáze: | OpenAIRE |
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