Cephamycins, a New Family of β-Lactam Antibiotics I. Production by Actinomycetes, Including Streptomyces lactamdurans sp. n
| Autor: | M. Jackson, Sheldon B. Zimmerman, Mata Justo M, Sebastian Hernandez, Sagrario Mochales, H. B. Woodruff, Edward O. Stapley, David Hendlin, Sara A. Currie |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Pharmacology
Cefalotin Gram-negative bacteria biology medicine.drug_class Gram-positive bacteria Cephalosporin Antibiotics Microbial Sensitivity Tests Articles beta-Lactams biology.organism_classification Streptomyces Anti-Bacterial Agents Cephalosporins Microbiology Infectious Diseases polycyclic compounds medicine Actinomyces Pharmacology (medical) Cephamycins Bacteria medicine.drug |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 2:122-131 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.2.3.122 |
| Popis: | A number of actinomycetes isolated from soil were found to produce one or more members of a new family of antibiotics, the cephamycins, which are structurally related to cephalosporin C. The cephamycins were produced in submerged fermentation in a wide variety of media by one or more of eight different species of Streptomyces , including a newly described species, S. lactamdurans . These antibiotics exhibit antibacterial activity against a broad spectrum of bacteria which includes many that are resistant to the cephalosporins and penicillins. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|