The Relationship between Extensively Drug-Resistant Tuberculosis and Multidrug-Resistant Gram-Negative Bacilli
| Autor: | Xiao-chun He, Xian-xin Zhang, Guo-ru Yang, Huai-chen Li, Xiao-qi Zhang, Jiang-nan Zhao |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Tuberculosis medicine.drug_class Science Antibiotics Logistic regression Mycobacterium tuberculosis Internal medicine Tuberculosis Multidrug-Resistant Medicine Humans Hypoalbuminemia Tuberculosis Pulmonary Aged Retrospective Studies History of tuberculosis Multidisciplinary biology business.industry Extensively drug-resistant tuberculosis Retrospective cohort study Middle Aged medicine.disease biology.organism_classification Surgery Female business Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Vol 10, Iss 7, p e0134998 (2015) |
| ISSN: | 1932-6203 |
| Popis: | ObjectiveThe relationship between extensively drug-resistant tuberculosis (XDR-TB) and multidrug-resistant Gram-negative bacilli (MDR-GNB) is unclear. Identification of the relationship between XDR-TB and MDR-GNB would have important implications for patient care.MethodsWe conducted a retrospective study reviewing the records of patients admitted with a confirmed pulmonary TB from 2011 to 2014. To identify the relationship between XDR-TB and MDR-GNB, univariable comparison and multivariable logistic regression were performed.ResultsAmong 2962 pulmonary TB patients, 45(1.5%) patients had a diagnosis of XDR-TB. A total of 165 MDR-GNB strains were detected in 143 (4.8%) pulmonary TB patients. XDR-TB patients had a significantly higher occurrence of MDR-GNB than non-XDR-TB patients (24.4% vs. 4.5%; PConclusionsPatients with XDR-TB have a significantly higher risk of being affected by MDR-GNB pathogen. The underlying mechanism association warrant further studies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|