Disease severity and trigger factors in Danish children with atopic dermatitis:a nationwide study
| Autor: | Charlotte G. Mortz, Jacob P. Thyssen, Lone Skov, Trine Gerner, Christian Vestergaard, Tove Agner, Gregor B.E. Jemec, M. Deleuran, Jeanette Halskou Haugaard, Alexander Egeberg |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Chlorinated water
Pediatrics medicine.medical_specialty Denmark Eczema MEDLINE CHILDHOOD Dermatology GUIDELINES Severity of Illness Index FOOD ALLERGY ORIENTED ECZEMA MEASURE Dermatitis Atopic Danish 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Disease severity Surveys and Questionnaires 030225 pediatrics Severity of illness MANAGEMENT Humans Medicine Child business.industry PATIENT PERSPECTIVES Atopic dermatitis medicine.disease language.human_language PREVALENCE Infectious Diseases CLINICAL-PRACTICE language RISK-FACTORS Hay fever ASTHMA Female business Multiple body regions |
| Zdroj: | Gerner, T, Haugaard, J H, Vestergaard, C, Deleuran, M, Jemec, G B, Mortz, C G, Agner, T, Egeberg, A, Skov, L & Thyssen, J P 2021, ' Disease severity and trigger factors in Danish children with atopic dermatitis : a nationwide study ', Journal of the European Academy of Dermatology and Venereology, vol. 35, no. 4, pp. 948-957 . https://doi.org/10.1111/jdv.17007 Gerner, T, Haugaard, J H, Vestergaard, C, Deleuran, M, Jemec, G B, Mortz, C G, Agner, T, Egeberg, A, Skov, L & Thyssen, J P 2021, ' Disease severity and trigger factors in Danish children with atopic dermatitis : a nationwide study ', Journal of The European Academy of Dermatology and Venereology, vol. 35, no. 4, pp. 948-957 . https://doi.org/10.1111/jdv.17007 |
| DOI: | 10.1111/jdv.17007 |
| Popis: | BACKGROUND: Atopic dermatitis (AD) is a prevalent chronically relapsing inflammatory skin disease of childhood. However, little is known about self-reported trigger factors, impact on daily life and factors associated with AD severity.METHODS: A nationwide questionnaire study of children in Denmark with hospital-diagnosed AD in the time period 2014-2018. The web-based questionnaire was completed by the legal parents. AD severity was assessed using Patient-Oriented Eczema Measure (POEM) tool.RESULTS: Of 3438 invited parents, 1343 (39%) completed the questionnaire. Factors associated with severe AD were onset during the first 6 months of life, onset of AD on multiple body regions, a history of hay fever, female sex and low maternal educational level. Staying home from daycare or school due to AD, concentration problems and sleep disturbances in the child were more frequently reported by parents to children with severe AD. Overall, 90% reported at least one AD trigger factor, and all were more frequently reported in children with severe AD. The three most commonly reported trigger factors were cold weather (51.9%), chlorinated water (35.7%) and warm weather (30.2%).CONCLUSIONS: We identified factors associated with severe AD in childhood, the impact on daily life, as well as the most common self-reported triggers of AD. These findings may be valuable in clinical practice to inform about prognosis and educate families about trigger avoidance. |
| Databáze: | OpenAIRE |
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