Retinal Sensitivity Correlates With the Superficial Vessel Density and Inner Layer Thickness in Diabetic Retinopathy
| Autor: | Carlo Lavia, Sophie Bonnin, Abir Zureik, azzeddine Mokrane, Ali Erginay, Alain Gaudric, Ramin Tadayoni, Aude Couturier |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Fovea Centralis genetic structures retinal sensitivity Retina optical coherence tomography-angiography (OCT-A) chemistry.chemical_compound Young Adult Vessel density Ophthalmology Medicine diabetic retinopathy (DR) Humans Fluorescein Angiography Macular edema Decibel Aged Aged 80 and over Diabetic Retinopathy business.industry Retinal Vessels Retinal Diabetic retinopathy capillary density Middle Aged medicine.disease eye diseases medicine.anatomical_structure chemistry Inner nuclear layer microperimetry Visual Field Tests Female sense organs business Sensitivity (electronics) Microperimetry Tomography Optical Coherence |
| Zdroj: | Investigative Ophthalmology & Visual Science |
| ISSN: | 1552-5783 0146-0404 |
| Popis: | Purpose The purpose of this paper was to present our study on the relationship between the parafoveal sensitivity measured using microperimetry and the vessel density (VD) assessed by optical coherence tomography-angiography (OCT-A) in eyes with diabetic retinopathy (DR). Methods The observational case series was conducted in a tertiary ophthalmology center. Eyes with DR and without macular edema were consecutively included. All eyes underwent microperimetry and OCT-A. The correlation between the regional retinal sensitivity and the corresponding local capillary changes and structural alterations seen on OCT-A was assessed in each retinal quadrant. Results Thirty-seven eyes of 21 patients were included. The mean retinal sensitivity was 28.7 ± 2 decibel (dB). The mean parafoveal VD was 43.2 ± 4.2% in the superficial capillary plexus (SCP) and 48.1 ± 3.3% in the deep capillary complex (DCC). In the multivariate linear regression model, the mean retinal sensitivity was positively correlated with the VD in the SCP in the parafoveal ring (P = 0.01) and with the inner nuclear layer (INL) thickness (P = 0.01). The qualitative analysis of each quadrant showed the presence of areas of capillary dropout with a normal sensitivity. Conversely, all areas of decreased sensitivity ( |
| Databáze: | OpenAIRE |
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