A community survey of antibiotic consumption among children in Madagascar and Senegal: the importance of healthcare access and care quality
| Autor: | Michael Padget, Awa Ndir, Fatoumata Diene Sarr, Didier Guillemot, Patrice Piola, Vincent Richard, Elisabeth Delarocque-Astagneau, Jeanne Tamarelle, Perlinot Herindrainy |
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| Přispěvatelé: | Biostatistique, Biomathématique, Pharmacoépidémiologie et Maladies Infectieuses (B2PHI), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Unité d'Epidémiologie [Antananarivo, Madagascar] (IPM), Institut Pasteur de Madagascar, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Institut Pasteur de Dakar, Réseau International des Instituts Pasteur (RIIP), Hôpital Raymond Poincaré [AP-HP], This work was undertaken as part of the Bacterial Infections and antibiotic Resistant Diseases among Young children (BIRDY) project (http://www.birdyprogram.org/), which is made possible by the funding of the Department of International Cooperation of the Principality of Monaco.This work has also received funding from the French Government’s Investissement d’Avenir programme, Laboratoire d'Excellence ‘IntegrativeBiology of Emerging Infectious Diseases’ (grant no. ANR-10-LABX-62-IBEID), the Epidemiology and Infectious Disease Unit of the InstitutePasteur of Dakar, and the Foundation Pierre Ledoux – Jeunesse Internationale., on behalf of the BIRDY Study Group, ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Solofoharivelo, Marie Chrystine, Integrative Biology of Emerging Infectious Diseases - - IBEID2010 - ANR-10-LABX-0062 - LABX - VALID, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Biostatistique, Biomathématique, Pharmacoépidémiologie et Maladies Infectieuses ( B2PHI ), Université de Versailles Saint-Quentin-en-Yvelines ( UVSQ ) -Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Unité d'Epidémiologie [Antananarivo, Madagascar] ( IPM ), Institut Pasteur de Madagascar-Réseau International des Instituts Pasteur ( RIIP ), Institut Pasteur de Dakar-Réseau International des Instituts Pasteur ( RIIP ), AP-HP Hôpital Raymond Poincaré [Garches], This work was undertaken as part of the Bacterial Infections and antibioticResistant Diseases among Young children (BIRDY) project (http://www.birdyprogram.org/), which is made possible by the funding of theDepartment of International Cooperation of the Principality of Monaco.This work has also received funding from the French Government’sInvestissement d’Avenir programme, Laboratoire d′ Excellence ‘IntegrativeBiology of Emerging Infectious Diseases’ (grant no. ANR-10-LABX-62-IBEID), the Epidemiology and Infectious Disease Unit of the InstitutePasteur of Dakar, and the Foundation Pierre Ledoux – JeunesseInternationale., ANR-10-LABX-0062/10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases ( 2010 ) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Pediatrics Cross-sectional study madagascar Health Services Accessibility antibiotics MESH: Madagascar 0302 clinical medicine [STAT.AP] Statistics [stat]/Applications [stat.AP] Drug Resistance Multiple Bacterial Surveys and Questionnaires Health care Medicine Pharmacology (medical) 030212 general & internal medicine MESH: Quality of Health Care Practice Patterns Physicians' MESH: Drug Utilization MESH: Developing Countries ComputingMilieux_MISCELLANEOUS 2. Zero hunger child MESH: Health Services Accessibility [STAT.AP]Statistics [stat]/Applications [stat.AP] MESH: Infant Anti-Bacterial Agents 3. Good health [ SDV.MHEP.MI ] Life Sciences [q-bio]/Human health and pathology/Infectious diseases Infectious Diseases community Female Microbiology (medical) medicine.medical_specialty [SDV.SP.MED] Life Sciences [q-bio]/Pharmaceutical sciences/Medication 030231 tropical medicine Developing country Pharmacy 03 medical and health sciences Antibiotic resistance MESH: Cross-Sectional Studies [SDV.SP.MED]Life Sciences [q-bio]/Pharmaceutical sciences/Medication MESH: Senegal senegal Environmental health MESH: Anti-Bacterial Agents Humans Medical prescription MESH: Surveys and Questionnaires Developing Countries Quality of Health Care Pharmacology Consumption (economics) MESH: Humans business.industry Public health Infant MESH: Drug Resistance Multiple Bacterial Drug Utilization MESH: Male Cross-Sectional Studies [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie MESH: Practice Patterns Physicians' [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business MESH: Female |
| Zdroj: | Journal of Antimicrobial Chemotherapy Journal of Antimicrobial Chemotherapy, 2017, 72 (2), pp.564-573. ⟨10.1093/jac/dkw446⟩ Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2017, 72 (2), pp.564-573. ⟨10.1093/jac/dkw446⟩ Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2017, 72 (2), pp.564-573. 〈10.1093/jac/dkw446〉 |
| ISSN: | 0305-7453 1460-2091 |
| DOI: | 10.1093/jac/dkw446⟩ |
| Popis: | International audience; Background: Antibiotic resistance is growing in low-income countries (LICs). Children in LICs are particularly at risk. Information on antibiotic consumption is needed to control the development and spread of resistant bacteria. Methods: To measure antibiotic consumption and related factors, a community survey was undertaken in two sites in Madagascar (Antananarivo and Moramanga) and in Senegal (Guediawaye) among children under 2. Face-to-face interviews were conducted with parents or caregivers of eligible children. Regression analysis was used to determine variables associated with reported antibiotic consumption. Availability of health structures and health policies were also investigated. Results: Population estimates for antibiotic consumption in the last 3 months were 37.2% (95% CI 33.4%–41.2%) in Guediawaye, 29.3% (95% CI 25.0%–34.1%) in Antananarivo and 24.6% (95% CI 20.6%–29.1%) in Moramanga. In all sites, the large majority of antibiotics were taken with a prescription (92.2%, 87.0% and 92.0% for Antananarivo, Moramanga and Guediawaye, respectively) and purchased in pharmacies (89.4%, 73.5% and 78.5%, respectively). Living in houses without flushing toilets and baby age were significantly associated with any antibiotic consumption after adjusting for site. A higher density of public health structures was associated with lower antibiotic consumption levels, while a higher density of private pharmacies was associated with higher levels across sites. Conclusions: These data are crucial for the implementation of local programmes aimed at optimizing antibiotic consumption. Factors such as density of healthcare facilities, prescriber training and national policy must be taken into account when developing strategies to optimize antibiotic consumption in LICs. |
| Databáze: | OpenAIRE |
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