Unravelling the Role of Electric and Magnetic Dipoles in Biosensing with Si Nanoresonators
| Autor: | Romain Quidant, Ozlem Yavas, Mikael Svedendahl |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Materials science
General Physics and Astronomy Context (language use) 02 engineering and technology Dielectric 010402 general chemistry 01 natural sciences law.invention law General Materials Science Absorption (electromagnetic radiation) Física [Àrees temàtiques de la UPC] Biosensing business.industry General Engineering Resonance Lab-on-a-chip 021001 nanoscience & nanotechnology 0104 chemical sciences Biosensors Extinction (optical mineralogy) Optoelectronics 0210 nano-technology business Magnetic dipole Biosensor |
| Zdroj: | UPCommons. Portal del coneixement obert de la UPC Universitat Politècnica de Catalunya (UPC) Recercat. Dipósit de la Recerca de Catalunya instname ACS Nano |
| ISSN: | 1936-086X 1936-0851 |
| DOI: | 10.1021/acsnano.9b00572 |
| Popis: | High refractive index dielectric nanoresonators are attracting much attention due to their ability to control both electric and magnetic components of light. Combining confined modes with reduced absorption losses, they have recently been proposed as an alternative to nanoplasmonic biosensors. In this context, we study the use of semi-random silicon nanocylinder arrays, fabricated with simple and scalable colloidal lithography for the efficient and reliable detection of biomolecules in biological samples. Interestingly, electric and magnetic dipole resonances are associated to two different transduction mechanisms: extinction decrease and resonance redshift, respectively. By contrasting both observables, we identify clear advantages in tracking changes in the extinction magnitude. Our data demonstrate that, despite its simplicity, the proposed platform is able to detect prostate specific antigen (PSA) in human serum with limits of detection meeting clinical needs. |
| Databáze: | OpenAIRE |
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