Kinetika reakcije 5-supstituisanih orotinskih kiselina sa dizaodifenilmetanom
| Autor: | Fathi H. Assaleh, Aleksandar D. Marinković, Bratislav Z. Jovanovic |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Steric effects
010405 organic chemistry Stereochemistry diazodiphenylmethane Kinetics Substituent General Chemistry reaction kinetics dimethylformamide 010402 general chemistry Resonance (chemistry) 01 natural sciences Medicinal chemistry 0104 chemical sciences lcsh:Chemistry Diazodiphenylmethane chemistry.chemical_compound Delocalized electron orotic acids Reaction rate constant chemistry lcsh:QD1-999 Dimethylformamide |
| Zdroj: | Journal of the Serbian Chemical Society, Vol 69, Iss 11, Pp 949-953 (2004) Journal of the Serbian Chemical Society |
| ISSN: | 1820-7421 0352-5139 |
| Popis: | Rate konstants for the reaction of eight 5-substituted orotic acids with diazodiphenylmethane (DDM) in dimethylformamide (DMF) were determined at 30 ºC by the known spectrophotometricmethod. The determined rate constants were correlated with the equations: logk2 = ασ1+βσR+h logk2 = ασ1+βσR+ψν+h to detect the presence and investigate the influence of both electrical and steric substituent effects. The obtained results show that the electrical effect (the localized – field and delocalized – resonance) is predominant and that the steric effect, althought present, is releatively small in this reaction. Konstante brzine za reakciju osam 5-spstituisanih orotinskih kiselina sa diazodifenilmetanom (DDM) određene su na 30 ºC u dimetilformamidu (DMF) kao rastvarač u, poznatom spektrofotometrijskim metodom. Konstante brzina ispitivanih reakcija korelisane su sledećim jednačinama: logk2 = ασ1+βσR+h logk2 = ασ1+βσR+ψν+h sa ciljem da se odrede efekti supstituenata. Dobijeni rezultati ukazuju na to da su električni efekti supstituenata (induktivni i rezonantni) preovlađujući, a da su sterni efekti supstituenata, iako su prisutni, u odnosu na njih relativno mali. |
| Databáze: | OpenAIRE |
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