Fractal construction of constrained code words for DNA storage systems

Autor:	Anne-Christin Hauschild, Dominik Heider, Georges Hattab, Marius Welzel, Hannah Franziska Löchel
Rok vydání:	2021
Předmět:	Fractals Genetics Computational Biology DNA
Zdroj:	Nucleic Acids Research. 50:e30-e30
ISSN:	1362-4962 0305-1048
DOI:	10.1093/nar/gkab1209
Popis:	The use of complex biological molecules to solve computational problems is an emerging field at the interface between biology and computer science. There are two main categories in which biological molecules, especially DNA, are investigated as alternatives to silicon-based computer technologies. One is to use DNA as a storage medium, and the other is to use DNA for computing. Both strategies come with certain constraints. In the current study, we present a novel approach derived from chaos game representation for DNA to generate DNA code words that fulfill user-defined constraints, namely GC content, homopolymers, and undesired motifs, and thus, can be used to build codes for reliable DNA storage systems.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a178bf330801af3d85ad2e10ae26af2 https://doi.org/10.1093/nar/gkab1209 Zobrazit plný text záznamu