Cocirculation of Two Distinct Groups of Influenza C Virus in Yamagata City, Japan
| Autor: | Hidekazu Nishimura, Yoko Matsuzaki, Kanetsu Sugawara, Kiyoto Nakamura, Fumio Kitame, Seiji Hongo, Yoshio Numazaki, Noriko Katsushima, Yasushi Muraki |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Viral Structural Proteins
Influenzavirus C Genes Viral Sequence Homology Amino Acid biology Orthomyxoviridae Oligonucleotides Nucleic acid sequence Hemagglutinins Viral Hemagglutinin Glycoproteins Influenza Virus biology.organism_classification Virology Virus Homology (biology) Japan Influenza Human Genetic structure Humans Amino Acid Sequence Viral disease Influenza C Virus Antigens Viral |
| Zdroj: | Virology. 202:796-802 |
| ISSN: | 0042-6822 |
| DOI: | 10.1006/viro.1994.1401 |
| Popis: | The antigenic and genetic relationships among 15 strains of influenza C virus isolated between August, 1988, and May, 1990, in Yamagata City, Japan, were investigated. Based on the results of antigenic analysis with monoclonal antibodies to the hemagglutinin-esterase (HE) glycoproteins and oligonucleotide mapping of total vRNA, the isolates were divided into two distinct groups closely related to either C/Yamagata/26/81 or C/Aichi/1/81. Antigenic differences between two groups could be detected clearly with heterogeneous antiviral sera. Comparison of the HE gene sequences between the representative Yamagata isolates and the previous isolates from other countries showed that C/Yamagata/26/81-like and C/Aichi/1/81-like viruses had high degrees of nucleotide sequence homology with C/pig/Beijing/115/81 and C/Johannesburg/1/66, respectively. These observations suggest that two lineages of influenza C virus, markedly different from each other in both antigenic and genetic structures, were simultaneously present in Yamagata City during 1988-1990 and that viruses belonging to each of the two lineages may also be prevalent in other areas of Japan and even in other countries. |
| Databáze: | OpenAIRE |
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