Bicyclic C21 Terpenoids from the Marine Sponge Clathria compressa
| Autor: | Thomas C. Schulz, Amanda B. McLean, Allan J. Robins, Prasoon Gupta, Upasana Sharma, Lyndon M. West |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Clathria
Stereochemistry Oceans and Seas Gram-positive bacteria Pharmaceutical Science Marine Biology Microbial Sensitivity Tests Gram-Positive Bacteria Article Analytical Chemistry Terpene Drug Discovery Botany Animals Pharmacology Molecular Structure biology Bicyclic molecule Terpenes Organic Chemistry biology.organism_classification Terpenoid Anti-Bacterial Agents Porifera Sponge Complementary and alternative medicine Molecular Medicine Antibacterial activity Bacteria |
| Zdroj: | Journal of Natural Products. 75:1223-1227 |
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/np300265p |
| Popis: | Three new bicyclic C(21) terpenoids, clathric acid (1) and two N-acyl taurine derivatives, clathrimides A (2) and B (3), were isolated from the marine sponge Clathria compressa. The structures of these compounds were elucidated by interpretation of spectroscopic data. Clathric acid showed mild antibacterial activity against several Gram-positive bacteria. |
| Databáze: | OpenAIRE |
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