Epileptic chorea: Another window into neural networks?
| Autor: | Mariana Holanda Gameleira, Kedma Mayara de Lima, Marcelo Andrés Kauffman, Fernando Tenório Gameleira, Alberto J. Espay, Karina Torres Alúcio, Maria Luísa Maia Nobre de Paiva, Kathleen Caroline de Lima Carlos |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
CIENCIAS MÉDICAS Y DE LA SALUD
Paroxysmal nonkinesigenic dyskinesia Artificial neural network business.industry Clinical Neurology Window (computing) Neurología Clínica Chorea CHOREA Medicina Clínica medicine.disease Epilepsy Neurology Medicine Neurology (clinical) medicine.symptom PAROXYSMAL NONKINESIGENIC DYSKINESIA business Neuroscience EPILEPSY |
| Popis: | Paroxysmal abnormalities of motor or non-motor function are defined as epileptic when they co-occur with specific patterns of organized electrical activity as measured by scalp electroencephalography (EEG). Certain forms of abdominal pain and migraine may be therefore epileptic [1]. Stereotypical movements at night can be the result of mesial frontal epilepsy, despite a negative EEG and prolonged focal paroxysmal dystonia can result from unilateral putaminal hemorrhage [2]. Short-lasting motor activity categorized clinically as dystonia or athetosis, meeting criteria for paroxysmal non-kinesigenic dyskinesia (PNKD), may result from caudate nucleus rather than cortical discharges [3,4]. These examples suggest that epileptic activity affecting different neural networks may manifest unique motor and non-motor clinical phenotypes, beyond the classic myoclonic or tonic-clonic motor phenomena attributed to cortical epilepsy. To this end, using video-EEG, we documented ictal discharges in the left temporal lobe of a patient with episodic chorea, initially suspected to be within the PNKD spectrum, suggesting that paroxysmal chorea can also be of epileptic origin in a subtype of patients. Fil: Gameleira, Fernando Tenório. Universidade Federal de Alagoas; Brasil Fil: Alúcio, Karina Torres. Universidade Federal de Alagoas; Brasil Fil: de Paiva, Maria Luísa Maia Nobre. Universidade Federal de Alagoas; Brasil Fil: de Lima Carlos, Kathleen Caroline. Universidade Federal de Alagoas; Brasil Fil: de Lima, Kedma Mayara. Universidade Federal de Alagoas; Brasil Fil: Gameleira, Mariana Holanda. Universidade Federal de Alagoas; Brasil Fil: Kauffman, Marcelo Andres. Universidad Austral. Facultad de Ciencias Biomédicas. Instituto de Investigaciones en Medicina Traslacional. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones en Medicina Traslacional; Argentina Fil: Espay, Alberto J.. University of Cincinnati; Estados Unidos |
| Databáze: | OpenAIRE |
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