A multi-integrated approach on toxicity effects of engineered TiO2 nanoparticles
| Autor: | Isabel Peres, António Pedro Alves Matos, Joana Castro Pereira, Joana Lourenço, Pedro Barquinha, J.B. Correia, Mário Diniz, Luisa Canto e Castro, Isabel M.P.L.V.O. Ferreira, Ana Picado, Luis F.O. Silva, Liliana Moita, Susana M. Paixão, E. Mendonça |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Transmission electron microscopy
Histology biology ecotoxicity Daphnia magna TiO2-nanoparticles Environmental exposure biology.organism_classification Toxicology Algae Biochemistry Aquatic plant transmission electron microscopy (TEM) Toxicity Ecotoxicology Titanium dioxide Nanoparticles Ecotoxicity Enzymatic analysis General Environmental Science EC50 |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| Popis: | The new properties of engineered nanoparticles drive the need for new knowledge on the safety, fate, behavior and biologic effects of these particles on organisms and ecosystems. Titanium dioxide nanoparticles have been used extensively for a wide range of applications, e.g, self-cleaning surface coatings, solar cells, water treatment agents, topical sunscreens. Within this scenario increased environmental exposure can be expected but data on the ecotoxicological evaluation of nanoparticles are still scarce. The main purpose of this work was the evaluation of effects of TiO2 nanoparticles in several organisms, covering different trophic levels, using a battery of aquatic assays. Using fish as a vertebrate model organism tissue histological and ultrastructural observations and the stress enzyme activity were also studied. TiO2 nanoparticles (Aeroxide® P25), two phase composition of anatase (65%) and rutile (35%) with an average particle size value of 27.6±11 nm were used. Results on the EC50 for the tested aquatic organisms showed toxicity for the bacteria, the algae and the crustacean, being the algae the most sensitive tested organism. The aquatic plant Lemna minor showed no effect on growth. The fish Carassius auratus showed no effect on a 21 day survival test, though at a biochemical level the cytosolic Glutathione-S-Transferase total activity, in intestines, showed a general significant decrease (p |
| Databáze: | OpenAIRE |
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