Water extract of Artemisia ordosica enhances antioxidant capability and immune response without affecting growth performance in weanling piglets
| Autor: | Shiwei Guo, Yuanqing Xu, Binlin Shi, Chenyu Mao, Yuan-yuan Xing, Xiao Jin, Sumei Yan, Ying-zhao Wu, Dengsheng Sun |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Antioxidant Globulin Swine 040301 veterinary sciences Feed additive medicine.medical_treatment Weanling Weight Gain Antioxidants 0403 veterinary science chemistry.chemical_compound Animal science Immune system Food Animals medicine Animals Animal nutrition biology Plant Extracts 0402 animal and dairy science Interleukin 04 agricultural and veterinary sciences Malondialdehyde Animal Feed 040201 dairy & animal science Diet Artemisia chemistry biology.protein Animal Nutritional Physiological Phenomena Female Animal Science and Zoology |
| Zdroj: | Journal of Animal Physiology and Animal Nutrition. 103:1848-1856 |
| ISSN: | 1439-0396 0931-2439 |
| DOI: | 10.1111/jpn.13171 |
| Popis: | The present experiment was conducted to investigate the effects of water extract of Artemisia ordosica (WEAO) on growth performance, antioxidant capability and immune response in weanling piglets. Seventy-two 28-day-old weanling piglets were randomly allocated into four treatments with six replicate pens per treatment and three piglets per pen (n = 18). These four treatment diets were formulated by adding 0, 250, 500 and 750 mg/kg WEAO to the basal diet. The experiment lasted for 28 days. Body weight and feed intake were measured. Blood samples were collected to determine immune and antioxidative parameters. The experimental results showed that WEAO supplementation improved the apparent nutrient digestibility of piglets in a linear or quadratic dose-dependent manner. In addition, dietary WEAO quadratically increased serum concentrations of cytokines interleukin (IL)-1, IL-4, tumour necrosis factor (TNF)-α, soluble surface antigen CD8 (sCD8), immunoglobulins (Ig)-A and linearly increased serum concentrations of IL-2, IL-6, IgG, IgM. Furthermore, dietary WEAO linearly or quadratically decreased serum concentrations of malondialdehyde but quadratically increased activities of antioxidant enzymes and total antioxidative capacity. These results suggested that WEAO may prove useful as a natural phytogenic feed additive with antioxidative potential and could be incorporated into diets of piglets. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text