Acetylcholinesterase in singly and multiply innervated muscles of normal and dystrophic chickens. II. Effects of denervation
| Autor: | Barry W. Wilson, T. A. Linkhart |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
medicine.medical_specialty
Fast twitch muscle Aché Biology Isozyme Tonic (physiology) chemistry.chemical_compound Internal medicine medicine Animals Cholinesterases Muscular dystrophy Poultry Diseases Denervation Muscles Dystrophy General Medicine Muscular Dystrophy Animal musculoskeletal system medicine.disease Acetylcholinesterase language.human_language body regions Endocrinology chemistry language Animal Science and Zoology Chickens |
| Zdroj: | Journal of Experimental Zoology. 193:191-200 |
| ISSN: | 1097-010X 0022-104X |
| DOI: | 10.1002/jez.1401930208 |
| Popis: | Neural regulation of mature normal fast twitch muscle of the chicken suppresses high activity, extrajunctional localization, and isozyme forms of acetylcholinesterase (AChE) characteristic of embryonic, denervated and dystrophic muscle. Normal adult slow tonic muscle of the chicken retains intermediate levels of activity and embryonic isozyme forms but not extrajunctional activity; it is not affected by muscular dystrophy. The hypothesis that neural regulation of the AChE system is lacking in slow tonic muscle and thus not affected by dystrophy was tested by denervating the fast twitch posterior latissimus dorsi and slow tonic anterior latissimus dorsi muscles of normal and dystrophic chickens. Extrajunctional AChE activity and embryonic isozyme forms increased, then declined, in both muscles. The results suggest that control of AChE is qualitatively similar in slow tonic and fast twitch muscle of the chicken. |
| Databáze: | OpenAIRE |
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