Obsessive compulsive symptoms associated with quetiapine treatment in a schizophrenic patient: A case report

Autor: Başaran Demir, Murat Arsava, Aygiin Ertugrul, Suzan Özer
Rok vydání: 2006
Předmět:
Zdroj: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 30:724-727
ISSN: 0278-5846
DOI: 10.1016/j.pnpbp.2005.11.030
Popis: Purpose Atypical antipsychotics (AAPs) are used as adjunct therapy in the treatment of resistant obsessive-compulsive symptoms (OCSs). Paradoxically other reports suggest that AAPs, particularly clozapine, risperidone, and olanzapine can induce de novo emergence or exacerbation of OCSs in psychotic patients. The authors present here the first report suggesting an association between de novo appearance of OCSs and quetiapine treatment in a schizophrenic patient. Case The patient was a 33-year-old woman with the diagnosis of paranoid schizophrenia, who displayed OCSs for the first time during treatment with quetiapine. The symptoms reduced remarkably when fluoxetine was added to her treatment regimen while keeping the quetiapine dosage unchanged. Conclusion AAP-induced OCSs merit consideration and early identification, as these drugs are now widely in use in clinical practice. This rare but disabling side effect should also be monitored in quetiapine treated schizophrenic patients.
Databáze: OpenAIRE