Effect of inspiratory flow waveform on work on endotracheal tubes: a model analysis

Autor: Andrea Rossi, Joseph Milic-Emili, E. D'Angelo, Guido Polese
Rok vydání: 1999
Předmět:
Zdroj: Intensive Care Medicine. 25:503-507
ISSN: 1432-1238
0342-4642
DOI: 10.1007/s001340050888
Popis: Objective: This model analysis aimed to predict the impact of different inspiratory flow waveforms, i. e., constant, sinusoidal, and two linearly decreasing flows, on the resistive work (Wres) performed on endotracheal tubes. Design: Model analysis. Results: Model analysis predicts that: (i) minimal Wres is obtained with the constant flow; (ii) for any given tidal volume/inspiratory duration (Vt/Ti, mean inspiratory flow), Wres increases with decreasing tube size; (iii) for any given inspiratory flow waveform, Wres increases with increasing Vt/Ti, being lowest with constant flow. Conclusions: These findings have major clinical implications: at any given ventilator setting, not only the size of the endotracheal tube but also the inspiratory flow waveform must be taken into account to interpret the values of Wres and hence of the total work of breathing.
Databáze: OpenAIRE