Applications of a travelling wave-based radio-frequency-only stacked ring ion guide
| Autor: | Kevin Giles, Steven Derek Pringle, Robert Harold Bateman, Kenneth R. Worthington, David Little, Jason Lee Wildgoose |
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| Rok vydání: | 2004 |
| Předmět: |
Ions
Spectrometry Mass Electrospray Ionization Ion thruster Radio Waves Chemistry Organic Chemistry Analytical chemistry Equipment Design Ion gun Mass spectrometry Analytical Chemistry Ion Equipment Failure Analysis Physics::Plasma Physics Duty cycle Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization Electrode Computer-Aided Design Feasibility Studies Radio frequency Atomic physics Spectroscopy Radio wave |
| Zdroj: | Rapid Communications in Mass Spectrometry. 18:2401-2414 |
| ISSN: | 1097-0231 0951-4198 |
| DOI: | 10.1002/rcm.1641 |
| Popis: | The use of radio-frequency (RF)-only ion guides for efficient transport of ions through regions of a mass spectrometer where the background gas pressure is relatively high is widespread in present instrumentation. Whilst multiple collisions between ions and the background gas can be beneficial, for example in inducing fragmentation and/or decreasing the spread in ion energies, the resultant reduction of ion axial velocity can be detrimental in modes of operation where a rapidly changing influx of ions to the gas-filled ion guide needs to be reproduced at the exit. In general, the RF-only ion guides presently in use are based on multipole rod sets. Here we report investigations into a new mode of ion propulsion within an RF ion guide based on a stack of ring electrodes. Ion propulsion is produced by superimposing a voltage pulse on the confining RF of an electrode and then moving the pulse to an adjacent electrode and so on along the guide to provide a travelling voltage wave on which the ions can surf. Through appropriate choice of the travelling wave pulse height, velocity and gas pressure it will be shown that the stacked ring ion guide with the travelling wave is effective as a collision cell in a tandem mass spectrometer where fast mass scanning or switching is required, as an ion mobility separator at pressures around 0.2 mbar, as an ion delivery device for enhancement of duty cycle on an orthogonal acceleration time-of-flight (oa-TOF) mass analyser, and as an ion fragmentation device at higher wave velocities. |
| Databáze: | OpenAIRE |
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