A transcriptional complex of NGATHA and bHLH transcription factors directs stigma development in Arabidopsis
| Autor: | Patricia Ballester, Cristina Ferrándiz, M Angeles Martinez-Godoy, Manuel Rodríguez-Concepción, Miguel Ezquerro, Marisa Navarrete-Gómez, Marina Trigueros |
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| Přispěvatelé: | Ministerio de Economía y Competitividad (España), Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), European Commission |
| Rok vydání: | 2021 |
| Předmět: |
Gynoecium
AcademicSubjects/SCI01270 AcademicSubjects/SCI01280 biology AcademicSubjects/SCI02288 AcademicSubjects/SCI02287 AcademicSubjects/SCI02286 Stigma (botany) Cell Biology Plant Science BHLH Transcription Factors Computational biology Physical interaction biology.organism_classification Arabidopsis Arabidopsis thaliana Transcription factor Research Articles Function (biology) |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname The Plant Cell RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia |
| ISSN: | 1532-298X 1040-4651 |
| DOI: | 10.1093/plcell/koab236 |
| Popis: | The stigma is an angiosperm-specific tissue that is essential for pollination. In the last two decades, several transcription factors with key roles in stigma development in Arabidopsis thaliana have been identified. However, genetic analyses have thus far been unable to unravel the precise regulatory interactions among these transcription factors or the molecular basis for their selective roles in different spatial and temporal domains. Here, we show that the NGATHA (NGA) and HECATE (HEC) transcription factors, which are involved in different developmental processes but are both essential for stigma development, require each other to perform this function. This relationship is likely mediated by their physical interaction in the apical gynoecium. NGA/HEC transcription factors subsequently upregulate INDEHISCENT (IND) and SPATULA and are indispensable for the binding of IND to some of its targets to allow stigma differentiation. Our findings support a nonhierarchical regulatory scenario in which the combinatorial action of different transcription factors provides exquisite temporal and spatial specificity of their developmental outputs. This work was supported by the Spanish Ministerio de Economia y Competitividad (grant BIO2015-64531-R to C.F.) and the Spanish Ministerio de Ciencia, Innovación y Universidades (grant RTI2018-099239-B-I00 to C.F.). |
| Databáze: | OpenAIRE |
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