Fish oil supplementation improves docosahexaenoic acid status of malnourished infants
| Autor: | E. N. Smit, E. A. Oelen, E. R. Boersma, Frits A. J. Muskiet, E. Seerat |
|---|---|
| Přispěvatelé: | Lifestyle Medicine (LM) |
| Jazyk: | angličtina |
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
Erythrocytes Docosahexaenoic Acids Protein–energy malnutrition Linolenic acid MARINE-OIL LINOLENIC ACID VISUAL-ACUITY DEVELOPMENT malnutrition fish oil chemistry.chemical_compound Fish Oils Animal science PRETERM INFANTS medicine PROTEIN-ENERGY MALNUTRITION Humans chemistry.chemical_classification POLYUNSATURATED FATTY-ACIDS HUMAN-MILK business.industry PLASMA-LIPIDS Infant Fatty acid ARACHIDONIC-ACID medicine.disease Fish oil Nutrition Disorders Surgery Breast Feeding Community Child Health Public Health and Epidemiology chemistry Docosahexaenoic acid Child Preschool Dietary Supplements Pediatrics Perinatology and Child Health Arachidonic acid erythrocyte business Breast feeding TERM INFANTS Polyunsaturated fatty acid long chain polyunsaturated fatty acids |
| Zdroj: | Archives of Disease in Childhood, 82(5), 366-369. BMJ PUBLISHING GROUP |
| ISSN: | 0003-9888 |
| Popis: | Aim-To investigate whether the low docosahexaenoic acid (DHA) status of malnourished, mostly breast fed, Pakistani children can be improved by fish oil (FO) supplementation.Methods-Ten malnourished children (aged 8-30 months) received 500 mg FO daily for nine weeks. The supplement contained 62.8 mol% (314 mg) long chain polyunsaturated fatty acids of the omega 3 series (LCPUFA omega 3) and 22.5 mol% (112 mg) DHA. Seven FO unsupplemented children served as controls. Red blood cell (RBC) fatty acids were analysed at baseline and at the study end.Results-FO supplementation augmented mean (SD) RBC DHA from 2.27 (0.81) to 3.35 (0.76) mol%, without significantly affecting the concentrations of LCPUFA omega 6. Unsupplemented children showed no RBC fatty acid changes. One FO supplemented child with very low initial RBC arachidonic acid showed a remarkable increase from 4.04 to 13.84 mol%, whereas another with high RBC arachidonic acid showed a decrease from 15.64 to 10.46 mol%.Conclusion-FO supplementation improves the DHA status of malnourished children. The supplement is apparently well absorbed and not exclusively used as a source of energy. |
| Databáze: | OpenAIRE |
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