Preoperative Serum Level of Vitamin D is a Possible Protective Factor for Peritumoral Brain Edema of Meningioma: A Cross Sectional Study
| Autor: | Alireza Zali, Zahra Vahdat Shariatpanahi, Melika Hajimohammadebrahim-Ketabforoush, Mohammadreza Shahmohammadi |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Vitamin Cancer Research Pathology medicine.medical_specialty Cross-sectional study Protective factor Medicine (miscellaneous) Brain Edema Blood–brain barrier Meningioma 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Meningeal Neoplasms Vitamin D and neurology Humans Medicine Vitamin D Peritumoral Brain Edema 030109 nutrition & dietetics Nutrition and Dietetics business.industry food and beverages Protective Factors medicine.disease Magnetic Resonance Imaging Cross-Sectional Studies medicine.anatomical_structure Oncology chemistry Nuclear receptor 030220 oncology & carcinogenesis business |
| Zdroj: | Nutrition and Cancer. 73:2842-2848 |
| ISSN: | 1532-7914 0163-5581 |
| Popis: | Meningioma is associated with the development of vasogenic edema defined as disrupted blood brain barrier. Vitamin D3 through its own nuclear receptor can regulate the expression of many effective agents on the integrity of the blood brain barrier. This study aimed to investigate the association between preoperative serum levels of 25(OH)D and peritumoral brain edema in patients with meningioma. One hundred and twelve patients with meningioma completed the study. Serum 25(OH)D levels assessment and magnetic resonance imaging (MRI) were done for all patients at the beginning of the study. The percentage of edema index (EI) was used to estimate the extent of peritumoral brain edema through preoperative MRI. The median serum level of 25(OH)D in the patients with the percentage of EI100% was significantly higher than those with100% (65.58 vs. 37.33 |
| Databáze: | OpenAIRE |
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