Clinical and manometric investigation in constipated Chagasic patients with and without megacolon
| Autor: | Paula Chrystina Caetano Almeida Leite, Marise Amaral Rebouças Moreira, Maria Alves Barbosa, Arminda Caetano de Almeida e Leite, José Paulo Teixeira Moreira, Hélio Moreira Júnior |
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| Rok vydání: | 2019 |
| Předmět: |
Reflexo
Chagas disease medicine.medical_specialty Constipation RC799-869 Megacolon Gastroenterology Doença de Chagas Internal medicine Diagnosis Reflex parasitic diseases medicine Canal anal Barium enema Chronic constipation business.industry Diagnóstico Megarectum Incidence (epidemiology) Ausência Diseases of the digestive system. Gastroenterology medicine.disease Constipação intestinal Chagas' disease Anal Exact test medicine.symptom business Absent |
| Zdroj: | Journal of Coloproctology (Rio de Janeiro), Volume: 39, Issue: 2, Pages: 145-152, Published: 13 JUN 2019 Journal of Coloproctology (Rio de Janeiro) v.39 n.2 2019 Journal of Coloproctology (Rio de Janeiro. Online) Sociedade Brasileira de Coloproctologia (SBCP) instacron:SBCP Journal of Coloproctology, Vol 39, Iss 2, Pp 145-152 (2019) |
| ISSN: | 2317-6423 2237-9363 |
| DOI: | 10.1016/j.jcol.2018.12.002 |
| Popis: | Background: Chagasic colopathy is the second most common digestive manifestation, and constipation is the main symptom. The absence of the Rectoanal Inhibitory Reflex plays an important role in constipation and anal manometry is crucial for appropriate evaluation. Purpose: Evaluate anal manometry findings (mainly Rectoanal Inhibitory Reflex) in Chagasic patients with chronic constipation, with and without megacolon and correlate these findings with clinical and demographic data. Methods: Cross-sectional study of patients with chronic constipation who underwent Chagasic serologic test, barium enema, and anal manometry. The absence of Rectoanal Inhibitory Reflex was evaluated using the mid-P Exact Test. Results: 64 Patients were included: 23 Chagasic patients with megacolon/megarectum (G1), 21 Chagasic patients without megacolon/megarectum (G2) and 20 non-Chagasic patients without megacolon/megarectum (G3). Chagasic patients with megacolon had a higher incidence of fecaloma (39%) compared to the other two groups (9.5% and 10% for G2 and G3, respectively, p = 0.03). Rectal capacity on manometry was statically higher for G1 patients. Rectoanal Inhibitory Reflex was absent in 91.3% of patients in G1, 47.29% in G2 and present in all patients in G3. There was a significant difference in the absence of the Rectoanal Inhibitory Reflex when comparing the groups (G1 vs. G2: p = 0.002, G1 vs. G3: p |
| Databáze: | OpenAIRE |
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