Analysis of patient repositioning accuracy in precision radiation therapy using automated image fusion
| Autor: | Jason Schella, Brenda G. Clark, Chang Seon Kim, James Robar |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_treatment
stereotactic radiosurgery Radiosurgery computer.software_genre Translation (geometry) Sensitivity and Specificity radiation therapy Imaging phantom Standard deviation Immobilization Artificial Intelligence Voxel medicine Humans Radiation Oncology Physics Radiology Nuclear Medicine and imaging Instrumentation Image fusion Radiation intensity‐modulated radiation therapy Phantoms Imaging business.industry Reproducibility of Results Radiographic Image Enhancement Radiation therapy Subtraction Technique Coronal plane stereotactic radiotherapy Radiotherapy Conformal Nuclear medicine business computer Rotation (mathematics) |
| Zdroj: | Journal of Applied Clinical Medical Physics |
| ISSN: | 1526-9914 |
| DOI: | 10.1120/jacmp.v6i1.1998 |
| Popis: | This work describes a rapid and objective method of determining repositioning error during the course of precision radiation therapy using off-line CT imaging and automated mutual-information image fusion. The technique eliminates the variability associated with manual identification of anatomical landmarks by observers. A phantom study was conducted to quantify the accuracy of the image co-registration-based analysis itself. For CT voxel dimensions of 0.65 x 0.65 x1.0 mm3, the method is shown to detect translations with an accuracy of 0.5 mm in the anterior-posterior and lateral dimensions and 0.8 mm in the superior-inferior dimension. Phantom rotation in the coronal plane was detected to within 0.5 degrees of expected values. The analysis has been applied to eight radiotherapy patients at two independent clinics, each immobilized by the same system for cranial stereotactic radiotherapy and CT-imaged once per week over the five- to six-week course of treatment. Among all patients, the ranges of translation in the anterior-posterior, lateral, and superior-inferior dimensions were -0.91 mm to 0.77 mm, -0.66 mm to 1.02 mm, and -2.24 mm to 3.47 mm, respectively. Considering all patients and CT scans, the standard deviations of translation were 0.42 mm, 0.47 mm, and 1.36 mm in the anterior-posterior, lateral, and superior-inferior dimensions, respectively. The ranges of patient rotation about the superior-inferior, left-right, and anterior-posterior axes were -2.84 to 2.62 degrees, -1.74 degrees to 1.96 degrees, and -1.78 degrees to 1.42 degrees, respectively. |
| Databáze: | OpenAIRE |
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