Staphylococcal bacteremia in cancer patients: risk factors and outcome in 134 episodes prior to and after introduction of quinolones into infection prevention in neutropenia
| Autor: | E. Oravcova, A. Kunova, P. Koren, Bezáková I, K Torfs, Korec S, Stanislav Spanik, M. Studena, J. Lacka, E. Kukuckova, Krcméry, E. Grey, M Balaz, L. Helpianska, I. Krupova, Trupl J, I. Ilavska, K. Stopkova, S. Grausova |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Slovakia Neutropenia Bacteremia Drug resistance Anti-Infective Agents Risk Factors Internal medicine Neoplasms medicine Endocarditis Humans Risk factor Antibacterial agent Retrospective Studies Catheter insertion Leukopenia business.industry Incidence Drug Resistance Microbial Staphylococcal Infections medicine.disease Surgery Anti-Bacterial Agents Survival Rate Treatment Outcome Oncology Drug Therapy Combination Female medicine.symptom business Fluoroquinolones |
| Zdroj: | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 4(6) |
| ISSN: | 0941-4355 |
| Popis: | A total of 134 episodes of staphylococcal bacteremia (SBE) appearing among 9987 admissions, and 979 episodes of bacteremia in cancer patients within 5 years, were analyzed for risk factors, clinical course and outcome; 64 were monomicrobial and 70 polymicrobial. The most frequent risk factors were acute leukemia, catheter insertion, long-lasting neutropenia, and prior prophylaxis with quinolones. There was no significant difference between polymicrobial and monomicrobial SBE in risk factors. The two groups differed only in the source of bacteremia (gastrointestinal and respiratory-tract infections were more common in monomicrobial SBE) and etiology —Staphylococcus aureus appeared more frequently in monomicrobial than in polymicrobial bacteremia (20.3% compared to 4.3%,P |
| Databáze: | OpenAIRE |
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