Hypoglycemic Syncope Induced by a Combination of Cibenzoline and Angiotensin Converting Enzyme Inhibitor
| Autor: | Kunio Hiwada, Yuji Hara, Mareomi Hamada, Yuji Shigematsu, Takafumi Okura, Hidetoshi Hashida, Hideyuki Saeki, Akiyoshi Ogimoto, Tomoaki Ohtsuka, Go Hiasa |
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| Rok vydání: | 2001 |
| Předmět: |
Cardiomyopathy
Dilated Heart disease medicine.medical_treatment Angiotensin-Converting Enzyme Inhibitors Hypoglycemia Antiarrhythmic agent Syncope chemistry.chemical_compound Hypothyroidism medicine Humans cardiovascular diseases Adverse effect Aged biology business.industry Imidazoles Angiotensin-converting enzyme Dilated cardiomyopathy medicine.disease chemistry Enzyme inhibitor Cibenzoline Anesthesia Tachycardia Ventricular biology.protein Female Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents |
| Zdroj: | Japanese Heart Journal. 42:255-259 |
| ISSN: | 1348-673X 0021-4868 |
| Popis: | A 65-year-old Japanese woman with dilated cardiomyopathy, hypothyroidism and refractory sustained ventricular tachycardia experienced a near-death hypoglycemic syncope. The attack seemed to be induced by a high level of serum insulin, probably due to cibenzoline and by concomitant use of an angiotensin converting enzyme inhibitor (ACEI). Additionally, decreased food intake because of a severe toothache may have contributed to the deterioration of her condition. This case warns cardiologists that a combined cibenzoline and ACEI therapy can provoke serious adverse effects such as hypoglycemic syncope in the elderly. Therefore, the possibility of a hypoglycemic attack associated with these drugs should be explained to patients who are in poor condition. |
| Databáze: | OpenAIRE |
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