Epileptic Encephalopathy and Autism: A Complex Interplay
| Autor: | Ashish Hanmantrao Chepure, Alka A Subramanyam, Ravindra K Kamath, Mansi Somaiya |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Occupational therapy
medicine.medical_specialty Pediatrics Antiepileptic drugs autism Case Report Electroencephalography 03 medical and health sciences Epilepsy 0302 clinical medicine Dravet syndrome Medicine medicine.diagnostic_test business.industry General Neuroscience Epileptic encephalopathy Cognition medicine.disease 030227 psychiatry epileptic encephalopathy Autism spectrum disorder Pediatrics Perinatology and Child Health Autism business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Pediatric Neurosciences |
| ISSN: | 1998-3948 1817-1745 |
| Popis: | Drug-resistant epileptic encephalopathy such as Dravet syndrome presents with autistic symptoms. Three cases with autism spectrum disorder with comorbid Dravet syndrome were assessed. All the cases presented with onset of seizures before a year and with autistic features. The patients responded to a combination of antiepileptic drugs (AEDs), resulting in reduced frequency of seizures and behavioral issues. Contrary to the belief that both epilepsy and use of AEDs have adverse impact on the cognition of children with an early onset of epilepsy, we found improvement in the symptoms of our patients who presented with autism and epilepsy. Primary treatment approaches such as occupational therapy, special education, speech therapy, and behavioral therapy; effective diagnosis of comorbidities such as epilepsy; and aggressive treatment might help with behavioral improvement. Early diagnosis followed by treatment with AEDs can improve seizures, electroencephalography abnormalities, and behavioral problems. |
| Databáze: | OpenAIRE |
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