Does pelvic inflammatory disease increase the risk for acquisition of human immunodeficiency virus type 1?
| Autor: | Kathleen L. Irwin, Tedd V. Ellerbrock |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
Human immunodeficiency virus (HIV) medicine.disease_cause Cervical ectopy Risk Factors Internal medicine HIV Seronegativity Pelvic inflammatory disease HIV Seropositivity medicine Immunology and Allergy Humans Sex organ Hiv acquisition Lower genital tract Hiv transmission Acquired Immunodeficiency Syndrome business.industry virus diseases Kenya Sex Work Infectious Diseases Immunology HIV-1 Female Vaginal pool business Pelvic Inflammatory Disease |
| Zdroj: | The Journal of infectious diseases. 172(3) |
| ISSN: | 0022-1899 |
| Popis: | Plourde et al. concluded that pelvic inflammatory disease (PID) may increase the risk of HIV-1 acquisition among Kenyan women with genital ulcers by six-fold. On the basis of their data however their conclusion seems premature. Upper and lower genital tract infections including PID may increase the risk of HIV acquisition because they may increase the cervical and vaginal pool of T lymphocytes and macrophages which are target cells of HIV. However until the relationship of PID and HIV is carefully examined in controlled epidemiologic clinical and laboratory studies the association of PID with HIV acquisition will be difficult to evaluate. Their report also concluded that cervical ectopy may increase by five-fold the risk of HIV acquisition in women with genital ulcers. Cervical ectopy may indeed play a role in heterosexual HIV transmission. Accurate and reliable methods of measuring ectopy and more knowledge about factors which affect the variability of ectopy are however needed before one can readily evaluate the association of cervical ectopy with HIV acquisition. |
| Databáze: | OpenAIRE |
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