METABOLITES OF HYDROCORTISONE AND CORTISONE IN SYNOVIAL FLUID IN RHEUMATOID ARTHRITIS*
| Autor: | Morris Ziff, Dominick Scialabba, Currier McEwen, Hildegard Wilson, Richard Fairbanks |
|---|---|
| Rok vydání: | 1956 |
| Předmět: |
medicine.medical_specialty
Hydrocortisone Endocrinology Diabetes and Metabolism medicine.medical_treatment Clinical Biochemistry Biochemistry Steroid Arthritis Rheumatoid Endocrinology Adrenal Cortex Hormones Internal medicine Synovial Fluid medicine Humans Synovial fluid Endocrine system Kidney Chemistry Arthritis Biochemistry (medical) Cortisone Steroid hormone medicine.anatomical_structure Adrenal Cortex medicine.drug Hormone |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 16:86-113 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-16-1-86 |
| Popis: | It Has been demonstrated that several tissues have the capacity to effect chemical transformations of added steroid hormones in vitro. Two recent reviews (1, 2) summarize much of the work pointing to the liver as a major site of catabolic changes, and to the kidney as also active in this respect. Other tissues appear to act on specific steroid compounds (3–8). When endocrine tissues transform added steroids to the characteristic active hormones of these tissues (6, 8) the process may be classed as biosynthetic rather than catabolic. The biosynthesis of adrenocortical hormones from inactive precursors by adrenal tissue has been amply demonstrated by the Worcester group and others (1, 9). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|