Transneuronal viral labelling of rat heart left ventricle controlling pathways
Autor: | G. Rakhorst, M. J. L. De Jongste, A. Van Den Brink, J. Korf, S. A. Homminga, Kong I. Lie, G. J. Ter Horst, Thomas C. Mettenleiter, Rwm Hautvast |
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Rok vydání: | 1993 |
Předmět: |
Male
Autonomic Fibers Preganglionic Heart Ventricles Biology Neural Pathways medicine Animals Ventricular Function Rats Wistar Nucleus ambiguus Catecholaminergic Pseudorabies General Neuroscience Myocardium Heart Anatomy Spinal cord Herpesvirus 1 Suid Immunohistochemistry Rats Autonomic nervous system medicine.anatomical_structure nervous system Spinal Cord Ventricle Circulatory system Medulla oblongata Nerve Net Cardiomyopathies Nucleus Paraventricular Hypothalamic Nucleus |
Zdroj: | Neuroreport. 4(12) |
ISSN: | 0959-4965 |
Popis: | Retrograde transneuronal viral labelling and immunocytochemical methods were used for revealing neuronal networks controlling the left ventricle myocardium of the rat heart. After injections of 1 microliter pseudorabies virus solution (3 x 10(6) PFU ml-1) into the left ventricle, infected orthosympathetic preganglionic cells were found in the intermediolateral cell groups of the first 6 thoracic spinal segments. Preganglionic parasympathetic neurones were seen both in the nucleus ambiguus/retro-ambiguus area and the dorsal motor vagus nucleus. Large numbers of infected projecting interneurones were found in the rostral, caudal and medial parts of the ventral medulla oblongata, the Kolliker-Fuse nucleus and catecholaminergic cell group A5 and in the paraventricular hypothalamic nucleus. |
Databáze: | OpenAIRE |
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