Inorganic nanoparticles for biomedicine: where materials scientists meet medical research
| Autor: | Juan J. Giner-Casares, Malou Henriksen-Lacey, Marc Coronado-Puchau, CIC BiomaGUNE, Luis M. Liz-Marzán |
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| Rok vydání: | 2016 |
| Předmět: |
Plasmonic nanoparticles
Materials science business.industry Mechanical Engineering Human immunodeficiency virus (HIV) Context (language use) Nanotechnology 02 engineering and technology Photothermal therapy 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics medicine.disease_cause Diagnostic tools Medical research 01 natural sciences 0104 chemical sciences Materials Science(all) Mechanics of Materials medicine General Materials Science 0210 nano-technology business Inorganic nanoparticles Biomedicine |
| Zdroj: | Materials Today. 19:19-28 |
| ISSN: | 1369-7021 |
| DOI: | 10.1016/j.mattod.2015.07.004 |
| Popis: | Materials scientists have performed exceptional accomplishments in the design of various types of materials that can be directly used for biomedical research. In particular, nanomaterials (including plasmonic nanoparticles) have become forefront scaffolds for designing bioactive materials. The application of such materials in biomedicine however requires a directed design providing actuation and stability in a particularly complex environment such as living organisms. Enhanced diagnostic tools for diseases such as cancer and HIV are pursued, and in this context nanoparticles offer exclusive physicochemical features for accurate biosensing, as well as actuation. We discuss the biosensing capabilities of plasmonic nanoparticles, in connection with SERS imaging. Novel therapies based on local drug delivery and photothermal therapy activated by nanoparticles are being explored. These applications are briefly discussed in this article, considering the actual biological problems faced by materials scientists and highlighting the beneficial interactions between materials science and biomedicine, which lead to novel routes in biomedical research and practice. |
| Databáze: | OpenAIRE |
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