Temporal trends in anaphylaxis ED visits over the last decade and the effect of COVID-19 pandemic on these trends
| Autor: | Adnan Al Ali, Sofianne Gabrielli, Luca Delli Colli, Marina Delli Colli, Christine McCusker, Ann E Clarke, Judy Morris, Jocelyn Gravel, Rodrick Lim, Edmond S. Chan, Ran D. Goldman, Andrew O’Keefe, Jennifer Gerdts, Derek K. Chu, Julia Upton, Elana Hochstadter, Jocelyn Moisan, Adam Bretholz, Xun Zhang, Jennifer LP Protudjer, Elissa M. Abrams, Elinor Simons, Moshe Ben-Shoshan |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Expert Review of Clinical Immunology. 19:341-348 |
| ISSN: | 1744-8409 1744-666X |
| Popis: | Anaphylaxis is an acute systemic and potentially fatal allergic reaction. In this study, we evaluated trends in yearly rates of anaphylaxis in a pediatric Emergency Department (ED) in Montreal, Canada.A prospective and retrospective recruitment process was used to find families of children who had presented with anaphylaxis at the Montreal Children's Hospital between April 2011 and April 2021. Using a uniform recruitment form, data were collected. Anaphylaxis patterns were compared to clinical triggers using descriptive analysis.Among 830,382 ED visits during the study period, 2726 (26% recruited prospectively) presented with anaphylaxis. The median age was 6 years (IQR: 0.2, 12.00), and 58.7% were males. The relative frequency of anaphylaxis cases doubled between 2011-2015, from 0.22% (95% CI, 0.19, 0.26) to 0.42 March 2020, the total absolute number of anaphylaxis cases and relative frequency declined by 24 cases per month (p0.05) and by 0.5% of ED visits (p0.05).The rate of anaphylaxis has changed over the years, representing modifications in food introduction strategies or lifestyle changes. The observed decrease in the frequency of anaphylaxis presenting to the ED during the COVID pandemic may reflect decreased accidental exposures with reduced social gatherings, the school closed, and reluctance to present to ED. |
| Databáze: | OpenAIRE |
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