Neutrophil/lymphocyte ratio is associated with right ventricular dysfunction in patients with acute inferior ST-segment elevation myocardial infarction
| Autor: | Rojhat Altındağ, Kemal Çevik, Erkan Baysal, Hüseyin Ede, Utkan Sevuk, Bernas Altıntaş, Barış Yaylak, Zülküf Karahan, Guney Erdogan, Şükrü Akyüz, Önder Bilge, Ender Ozgun Cakmak, Nuri Comert |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Neutrophils medicine.medical_treatment Lymphocyte Ventricular Dysfunction Right Inferior Wall Myocardial Infarction 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Percutaneous Coronary Intervention Predictive Value of Tests Risk Factors Internal medicine medicine Odds Ratio Humans In patient cardiovascular diseases 030212 general & internal medicine Myocardial infarction Inferior ST segment elevation Lymphocyte Count Lymphocytes Prospective Studies Neutrophil to lymphocyte ratio Aged Chi-Square Distribution Receiver operating characteristic business.industry fungi Percutaneous coronary intervention General Medicine Middle Aged medicine.disease medicine.anatomical_structure Logistic Models Treatment Outcome ROC Curve Area Under Curve Conventional PCI Multivariate Analysis Cardiology Ventricular Function Right Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cardiology journal. 23(1) |
| ISSN: | 1898-018X |
| Popis: | Background: Acute inferior ST-segment elevation myocardial infarction (STEMI) is associated with increased in-hospital morbidity and mortality particularly among patients with coexisting right ventricular (RV) involvement. High neutrophil to lymphocyte ratio (NLR) is an independent predictor of major adverse cardiac events and mortality in patients with myocardial infarction. This study evaluated the relationship between the NLR and RV dysfunction (RVD) in patients with inferior STEMI who underwent primary percutaneous coronary intervention (PCI). Methods: A total of 213 subjects with inferior STEMI were divided into two groups according to the presence of RVD. The groups were compared according to NLR and receiver operating characteristic (ROC) analysis was performed to access the predictability of NLR on having RVD. Results: The NLR was significantly higher in the group with RVD compared to that without RVD (p 3.5 predicted RVD with sensitivity of 83% and specificity of 55%. In a multivariate regression analysis, NLR remained an independent predictor of RVD (OR 1.55, 95% CI 1.285–1.750, p < 0.001). Conclusions: NLR was an independent predictor of RVD in patients with inferior STEMI undergoing primary PCI. |
| Databáze: | OpenAIRE |
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