Advanced bladder cancer: options of therapy
Autor: | Pontes Je |
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Rok vydání: | 1994 |
Předmět: |
Cancer Research
medicine.medical_specialty medicine.medical_treatment Disease Toxicology Cystectomy Antineoplastic Combined Chemotherapy Protocols medicine Carcinoma Humans Pharmacology (medical) Pharmacology Chemotherapy Carcinoma Transitional Cell Modalities Urinary bladder business.industry medicine.disease Combined Modality Therapy Surgery Radiation therapy medicine.anatomical_structure Oncology Urinary Bladder Neoplasms Chemotherapy Adjuvant Advanced bladder cancer Radiotherapy Adjuvant Radiology business Follow-Up Studies |
Zdroj: | Cancer chemotherapy and pharmacology. |
ISSN: | 0344-5704 |
Popis: | Little progress has been made on the treatment of invasive transitional-cell carcinoma over the last 30-40 years. The lack of accurate staging modalities, which carries approximately 20%-30% understaging and 20% overstaging, makes evaluation of small gains attributed to any forms of therapy questionable. Furthermore, the lack of proper comparative studies among the different options of therapy continues to confuse the issues [21]. In the United States, until recently, the traditional approach to invasive bladder tumor has been radical cystectomy. Although there is an excellent control of local disease with this approach, approximately half of the patients will die of metastatic disease following this procedure. In other countries, radiation therapy has been used as a traditional method of treating invasive disease. Recently, combinations of chemotherapy, radiation, and surgery have been tried in an attempt to improve the survival of patients with invasive cancer. Herein I discuss the different approaches to invasive bladder tumors and the recent reported results. |
Databáze: | OpenAIRE |
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