Advanced bladder cancer: options of therapy

Autor: Pontes Je
Rok vydání: 1994
Předmět:
Zdroj: Cancer chemotherapy and pharmacology.
ISSN: 0344-5704
Popis: Little progress has been made on the treatment of invasive transitional-cell carcinoma over the last 30-40 years. The lack of accurate staging modalities, which carries approximately 20%-30% understaging and 20% overstaging, makes evaluation of small gains attributed to any forms of therapy questionable. Furthermore, the lack of proper comparative studies among the different options of therapy continues to confuse the issues [21]. In the United States, until recently, the traditional approach to invasive bladder tumor has been radical cystectomy. Although there is an excellent control of local disease with this approach, approximately half of the patients will die of metastatic disease following this procedure. In other countries, radiation therapy has been used as a traditional method of treating invasive disease. Recently, combinations of chemotherapy, radiation, and surgery have been tried in an attempt to improve the survival of patients with invasive cancer. Herein I discuss the different approaches to invasive bladder tumors and the recent reported results.
Databáze: OpenAIRE