The Effects of Escalation of Respiratory Support and Prolonged Invasive Ventilation on Outcomes of Cardiac Surgical Patients: A Retrospective Cohort Study

Autor: Caroline Gerrard, Marc Giménez-Milà, Andrew Conway Morris, Ken Kuljit S. Parhar, Alain Vuylsteke, Vasileios Zochios, Andrew A. Klein, Joht Singh Chandan, Marcus J. Schultz
Přispěvatelé: Intensive Care Medicine, ACS - Diabetes & metabolism, ACS - Pulmonary hypertension & thrombosis, ACS - Microcirculation, Conway Morris, Andrew [0000-0002-3211-3216], Apollo - University of Cambridge Repository
Jazyk: angličtina
Rok vydání: 2020
Předmět:
medicine.medical_specialty
medicine.medical_treatment
Comorbidity
030204 cardiovascular system & hematology
Respiració artificial
Hypoxemia
law.invention
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Comorbiditat
030202 anesthesiology
law
invasive ventilation
medicine
Clinical endpoint
Humans
Continuous positive airway pressure
Cardiac Surgical Procedures
Retrospective Studies
Noninvasive Ventilation
business.industry
Retrospective cohort study
Perioperative
pulmonary morbidity
Length of Stay
Respiration
Artificial
Intensive care unit
Cardiac surgery
Heart surgery
Anesthesiology and Pain Medicine
Artificial respiration
Emergency medicine
Breathing
Cirurgia cardíaca
postoperative pulmonary complications
medicine.symptom
Cardiology and Cardiovascular Medicine
business
cardiac surgery
Zdroj: Journal of cardiothoracic and vascular anesthesia, 34(5), 1226-1234. W.B. Saunders Ltd
Dipòsit Digital de la UB
Universidad de Barcelona
ISSN: 1053-0770
Popis: Objectives: The aim of this study was to determine the effects of escalation of respiratory support and prolonged postoperative invasive ventilation on patient–centered outcomes, and identify perioperative factors associated with these two respiratory complications. Design: A retrospective cohort analysis of cardiac surgical patients admitted to cardiothoracic intensive care unit (ICU) between August 2015 and January 2018. Escalation of respiratory support was defined as ‘unplanned continuous positive airway pressure’, ‘non-invasive ventilation’ or ‘reintubation’ following surgery; prolonged invasive ventilation was defined as ‘invasive ventilation beyond the first 12 hours following surgery’. The primary endpoint was the composite of escalation of respiratory support and prolonged ventilation. Setting: Tertiary cardiothoracic ICU. Participants: A total of 2,098 patients were included and analyzed. Interventions: None. Measurements and Main Results: The composite of escalation of support or prolonged ventilation occurred in 509 patients (24.3%). Patients who met the composite had higher mortality (2.9% vs 0.1%; P
ACM is supported by a Clinical Research Career Development Fellowship from the Wellcome Trust (WT 2055214/Z/16/Z). VZ is supported by an Academic Clinical Fellowship from the National Institute for Health Research (ACF-2016-09-011).
Databáze: OpenAIRE
Externí odkaz: