Photographic estimation of the duration of high dose intravitreal triamcinolone in the vitrectomised eye
| Autor: | Lingyun Cheng, Brian R. Kosobucki, William R. Freeman |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Triamcinolone acetonide Pseudophakia genetic structures medicine.drug_class medicine.medical_treatment Anti-Inflammatory Agents Vitrectomy Clinical Science - Scientific Report Eye Triamcinolone Acetonide Macular Edema Injections Cellular and Molecular Neuroscience Endophthalmitis Ophthalmology Photography medicine Humans Prospective Studies Glucocorticoids Macular edema Aged business.industry Middle Aged Cataract surgery medicine.disease Survival Analysis eye diseases Sensory Systems Surgery Vitreous Body medicine.anatomical_structure Corticosteroid Female sense organs Choroid business Uveitis medicine.drug |
| Zdroj: | British Journal of Ophthalmology. 90:705-708 |
| ISSN: | 0007-1161 |
| DOI: | 10.1136/bjo.2005.088278 |
| Popis: | Aim: To determine the duration of residence of triamcinolone in the vitrectomised eye. Methods: 23 eyes of 23 patients underwent intravitreal injection of high dose (20 mg) decanted triamcinolone acetonide (Kenalog) at the conclusion of vitrectomy surgery or in previously vitrectomised eyes with macular oedema from diabetes, uveitis, cataract surgery, or other surgery. Results: The median time to disappearance of triamcinolone in the vitrectomised eye was 113 days (95% confidence interval (CI) 85 to 191). In the phakic eyes the median time to disappearance was 191 days (95% CI 148 to 191). In the pseudophakic eyes the median time to disappearance was 102 days (95% CI 85 to 113). This difference was not significant (p = 0.12). There were no cases of endophthalmitis or severe inflammatory reaction. Five eyes (22%) experienced intraocular pressure rise >10 mm Hg. Conclusions: High dose decanted intravitreal triamcinolone has a median residence time of 113 days in the vitrectomised eye. Although this appears to be shorter than in the nonvitrectomised eye, this study suggests that a sufficient duration of action will be present to be clinically useful. |
| Databáze: | OpenAIRE |
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