Effect and Outcome of Intraoperative Fluid Restriction in Living Liver Donor Hepatectomy
| Autor: | Chia-Jung Huang, Bruno Jawan, Chiu-En Huang, Kwok-Wai Cheng, Ying-En Lee, Tsung-Hsiao Shih, Sin-Ei Juang, Chih-Hsien Wang, Chao-Long Chen, Shao-Chun Wu, Sheng-Chun Yang |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Blood transfusion medicine.medical_treatment Blood Loss Surgical Renal function Liver transplantation 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine Living Donors Hepatectomy Humans Postoperative Period Retrospective Studies Transplantation Creatinine Intraoperative Care business.industry Central venous pressure General Medicine Perioperative Surgery Liver Transplantation Treatment Outcome chemistry 030220 oncology & carcinogenesis Anesthesia 030211 gastroenterology & hepatology Female Hemoglobin business |
| Zdroj: | Annals of transplantation. 22 |
| ISSN: | 2329-0358 |
| Popis: | BACKGROUND The purpose of this study was to evaluate the effect and outcome of intraoperative fluid restriction in living liver donor hepatectomy, regarding changes in intraoperative CVP levels, blood loss, and postoperative renal function. MATERIAL AND METHODS The charts of 167 patients were reviewed and analyzed retrospectively. Intraoperative central venous pressure levels, blood loss, fluids infused, and urine output per hour, before and after the liver allograft procurement, were calculated. Perioperative renal functions were also analyzed. RESULTS Fluid infused before and after liver allograft procurement was 3.21±1.5 and 9.0±3.9 mL/Kg/h and urine output was 1.5±0.7 and 1.8±1.4 mL/Kg/h, respectively. Intraoperative estimated blood loss was 91.3±78.9 mL. No patients required blood transfusion. Their preoperative and postoperative hemoglobin were 12.3±2.7 and 11.7±1.7 g/dL. CVP levels decreased gradually from 10.4±3.0 to a low of 8.1±1.9 mmHg at the time of transection of the liver parenchyma. Renal functions were not significantly affected based on the determination of BUN and creatinine levels. CONCLUSIONS The methods used to lower CVP are moderate and slow, with 2 main goals achieved: minimal blood loss (91.3±78.9 ml) and no blood transfusion. Furthermore, it did not have any negative effect on renal function. |
| Databáze: | OpenAIRE |
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