Renal clearance of I131 in hypothyroid and euthyroid rats
| Autor: | Jerome L. Gilbert, Gertrude Lange |
|---|---|
| Rok vydání: | 1955 |
| Předmět: |
medicine.medical_specialty
Hypophysectomy medicine.medical_treatment Renal function Estrone Urine Kidney Iodine Radioisotopes chemistry.chemical_compound Endocrinology Blood serum Hypothyroidism Internal medicine Medicine Animals Euthyroid business.industry Thyroid Rats medicine.anatomical_structure chemistry Renal physiology Cortisone business medicine.drug Iodine |
| Zdroj: | Endocrinology. 57(2) |
| ISSN: | 0013-7227 |
| Popis: | There have been numerous studies of variations in thyroidal uptake of radioactive iodine under varying biological conditions as a result of which it has been suggested that changes in renal clearance may also take place and affect the results. Thus Money et al. (1951) noted that ACTH, cortisone, Compound A, and DOC, decreased thyroid collection while testosterone, estrone, and progesterone increased collection of radioiodine. He admitted that the results possibly could be explained on the basis of steroid effects on water and salt metabolism and thus renal excretion of iodide. Randall and Albert (1951) in discussing the profound drop in thyroid uptake following hypophysectomy stated that part of the decrease may be due to factors other than the direct effect of hypophysectomy on the thyroid since the procedure might have affected renal function and hemodynamic conditions. Albert, Tenney and Lorenz (1952) found that renal clearance is markedly depressed after hypophysectomy |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|