Anti-inflammatory effect and the effect on acute pharyngitis rats model of compound Lobelia oral liquid
Autor: | Baosong Liu, Mingsan Miao, Ming Bai, Mengfan Peng |
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Rok vydání: | 2019 |
Předmět: |
0106 biological sciences
0301 basic medicine medicine.drug_class Lobelia Stimulation Pharmacology Acute Pharyngitis 01 natural sciences Article Anti-inflammatory 03 medical and health sciences White blood cell medicine Foot swelling lcsh:QH301-705.5 biology business.industry biology.organism_classification 030104 developmental biology medicine.anatomical_structure lcsh:Biology (General) Visual observation General Agricultural and Biological Sciences business 010606 plant biology & botany Egg white |
Zdroj: | Saudi Journal of Biological Sciences, Vol 26, Iss 3, Pp 577-581 (2019) |
ISSN: | 1319-562X |
DOI: | 10.1016/j.sjbs.2018.11.018 |
Popis: | Objective: Observe anti-inflammatory effect and the effect on acute pharyngitis rats model induced by ammonia water of compound Lobelia oral liquid, providing experimental basis for its clinical use. Methods: Use egg white establish foot swelling rats model and use carboxymethyl cellulose establish white blood cell migration rats model. Then observe the anti-inflammatory effect of compound Lobelia oral liquid. Use 15% ammonia spray at pharyngeal establish acute pharyngitis rats model, Visual observation and conduct grading of pharyngeal tissue stimulation in rats, measure the levels of TNF-α and IL-6 in serum. Pharyngeal tissue was taken to observe the morphological changes. Result: All dose groups of compound Lobelia oral liquid can reduce the rate of foot swelling of rats at all time points (P |
Databáze: | OpenAIRE |
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