Anti-inflammatory effect and the effect on acute pharyngitis rats model of compound Lobelia oral liquid

Autor: Baosong Liu, Mingsan Miao, Ming Bai, Mengfan Peng
Rok vydání: 2019
Předmět:
Zdroj: Saudi Journal of Biological Sciences, Vol 26, Iss 3, Pp 577-581 (2019)
ISSN: 1319-562X
DOI: 10.1016/j.sjbs.2018.11.018
Popis: Objective: Observe anti-inflammatory effect and the effect on acute pharyngitis rats model induced by ammonia water of compound Lobelia oral liquid, providing experimental basis for its clinical use. Methods: Use egg white establish foot swelling rats model and use carboxymethyl cellulose establish white blood cell migration rats model. Then observe the anti-inflammatory effect of compound Lobelia oral liquid. Use 15% ammonia spray at pharyngeal establish acute pharyngitis rats model, Visual observation and conduct grading of pharyngeal tissue stimulation in rats, measure the levels of TNF-α and IL-6 in serum. Pharyngeal tissue was taken to observe the morphological changes. Result: All dose groups of compound Lobelia oral liquid can reduce the rate of foot swelling of rats at all time points (P
Databáze: OpenAIRE