Covid-19 and HIV: Not Always an Unfavorable Combination

Autor: Pedro Vieira Bertozzi, João Pedro Espinha de Sant’Ana, Rafaela Braga Cabrera Mano, Luciana Souza Jorge, Amanda de Oliveira Vicente, Amanda Siqueira Pereira, Rodrigo Afonso da Silva Sardenberg
Rok vydání: 2020
Předmět:
DOI: 10.21203/rs.3.rs-99599/v1
Popis: Background: A 73-years-old-man patient who had a history of Human Immunodefiency Virus (HIV) infection for over 20 years was diagnosed with SARS-CoV-2 infection.Case presentation: The patient was admitted to the Intensive Care Unit (ICU), where he remained for 25 days, due to a severe condition. Intubation, hemodialysis and tracheostomy were necessary to maintain homeostasis. In addition to regular treatment with etravirine, dolutegravir, darunavir and ritonavir for highly active antiretroviral therapy, the patient received To-cilizumab, which showed a great recovery in the patient's condition.Conclusion : The patient had several risk factors, such as: male gender, age> 70 years and hypertension. The use of To-cilizumab was of great importance in the patient's recovery, since the drug increased his immune response, which is deficient, due to HIV infection.
Databáze: OpenAIRE