Tissue histamine levels and mast cell numbers in tumour-bearing mice
Autor: | C. Burtin, C. Ponvert, P. Canu, Geneviève Lespinats, Antoinette Fray, F. Raynaud, Pierre Scheinmann, L. Galoppin |
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Rok vydání: | 1984 |
Předmět: |
Male
medicine.medical_specialty Pathology Allergy Immunology Pharmacology toxicology Cell Count Biology Toxicology Mice chemistry.chemical_compound Internal medicine medicine Carcinoma Animals Pharmacology (medical) Mast Cells Fibrosarcoma Pharmacology Mice Inbred C3H Neoplasms Experimental medicine.disease Mast cell Mice Inbred C57BL medicine.anatomical_structure Endocrinology chemistry Female Thymidine Histamine |
Zdroj: | Agents and Actions. 14:494-496 |
ISSN: | 1420-908X 0065-4299 |
DOI: | 10.1007/bf01973857 |
Popis: | In C57BL/6 mice bearing the 3LL carcinoma and in C3H mice bearing the McC3 -1 fibrosarcoma (18th passage), the increase in skin histamine levels was correlated with the increase in mast cell number. The number of cells able to incorporate tritiated thymidine was proportional to the mast cell number. These results strengthen the notion that, in tumour-bearing rodents, the increase in tissue histamine is an active phenomenon. |
Databáze: | OpenAIRE |
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