Simplified PRISM III score and outcome in the pediatric intensive care unit
| Autor: | Gustavo Romero-Gutiérrez, Carlos Aldana Valenzuela, Ana Lilia Ponce Ponce de León, Francisco Ernesto González-Bravo |
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| Rok vydání: | 2005 |
| Předmět: |
Pediatrics
medicine.medical_specialty Poison control Intensive Care Units Pediatric Logistic regression Sensitivity and Specificity Severity of Illness Index Cohort Studies Cause of Death Infant Mortality medicine Risk of mortality Craniocerebral Trauma Humans Prospective Studies Prospective cohort study Developing Countries Mexico Pediatric intensive care unit Receiver operating characteristic business.industry Infant Newborn Infant Odds ratio Shock Septic Confidence interval Logistic Models Child Preschool Pediatrics Perinatology and Child Health business |
| Zdroj: | Pediatrics International. 47:80-83 |
| ISSN: | 1442-200X 1328-8067 |
| Popis: | Background: To evaluate the association of the PRISM III (pediatric risk of mortality) score with the infant outcome in the pediatric intensive care unit (PICU), and to determine if this score could be simplified. Methods: A prospective cohort study was carried out with 170 infants who were consecutively admitted to the PICU. The PRISM III score with 17 physiologic variables was performed during the first 8 h of admission to the unit. Statistical analysis was done with logistic regression, odds ratios (OR) with 95% confidence intervals (95% CI), and receiver operating curve. The Alfa value was set at 0.05. Results: There were 42 deaths (24.7%). The two main causes of death were septic shock (28.6%) and head trauma (16.7%). The PRISM III score had a sensitivity of 0.71, and a specificity of 0.64 as a mortality predictor. Out of the 17 physiologic variables only four of them were significant: abnormal pupillary reflexes OR 9.9 (95% CI, 3.5–28.4), acidosis OR 3.1 (95% CI, 2.0–4.9), blood urea nitrogen concentration OR 1.03 (95% CI, 1.01–1.04), and white blood cell count OR 1.02 (95% CI, 1.01–1.03). The whole logistic regression model had a coefficient of determination R2 = 0.219, P |
| Databáze: | OpenAIRE |
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