Low Colorectal Tumor Removal by E-Cadherin Destruction-Enabled Tumor Cell Dissociation

Autor:	Man Li, Qunqun Bao, Jing Guo, Ruting Xie, Chao Shen, Qing Wei, Ping Hu, Huanlong Qin, Jianlin Shi
Rok vydání:	2022
Předmět:	Cell Line Tumor Mechanical Engineering Tumor Microenvironment Humans General Materials Science Bioengineering General Chemistry Cadherins Colorectal Neoplasms Condensed Matter Physics Edetic Acid
Zdroj:	Nano Letters. 22:2769-2779
ISSN:	1530-6992 1530-6984
DOI:	10.1021/acs.nanolett.1c04797
Popis:	Treatments for low colorectal cancer (CRC) remain a great challenge due to the heavy physical and psychological burdens of colostomy, strong drug toxicity in chemotherapy, and myelosuppression-/chemoradiation-related gastrointestinal symptoms. In this study, a highly biosafe and effective tumor cell dissociation-based low CRC treatment modality has been verified on both PDOs
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c5cd08d4b0448e438874fa11211729 https://doi.org/10.1021/acs.nanolett.1c04797 Zobrazit plný text záznamu