Aztreonam concentrations in human tissues obtained during thoracic and gynecologic surgery
| Autor: | R. P. Galask, T. R. Beam, M. A. Leitz, T. B. Platt, L. T. Friedhoff |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Thorax
Pathology medicine.medical_specialty Premedication Ovary Aztreonam Endometrium chemistry.chemical_compound medicine Humans Pharmacology (medical) Aged Antibacterial agent Pharmacology urogenital system business.industry Muscles Myometrium Thoracic Surgery Pericardial fluid Middle Aged Body Fluids Surgery Infectious Diseases medicine.anatomical_structure chemistry Female business Genital Diseases Female Research Article Fallopian tube |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 30:505-507 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.30.3.505 |
| Popis: | The concentrations of aztreonam in human tissues obtained during surgery were measured after a single 2-g intravenous dose. The average concentration in the skeletal muscle, atrial appendage, lung, sternum, pericardial fluid, endometrium, myometrium, fallopian tube, and ovary varied from 3 to 33 micrograms/g (or microgram/ml). These concentrations significantly exceed the MIC for 90% of strains for most members of the family Enterobacteriaceae. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|