Extraparenchymal ovarian and testicular Leydig cells: ectopic/heterotopic or orthotopic?

Autor: Rafael Méndez-Medina, José L Carrasco-Juan, Hugo Álvarez-Argüelles-Cabrera, Idaira Expósito-Afonso, Lucio Díaz-Flores, Ricardo Gutiérrez-García, Carmen Martín-Corriente, Abián Vega-Falcón
Rok vydání: 2018
Předmět:
Zdroj: Archives of Gynecology and Obstetrics. 298:655-661
ISSN: 1432-0711
0932-0067
DOI: 10.1007/s00404-018-4846-x
Popis: We are conducting a prospective study trying to determine, in both sexes, the frequency of appearance of ectopic Leydig cells, their preferred location, their relationship with nerve structures and the possible causes of their appearance. We have studied 86 cases that were removed according to different clinical indications for pathological study: uterine leyomiomas (n = 12), ovarian cystadenoma (n = 4), endometrial hyperplasia (n = 8), endometrial carcinoma (n = 12), cervical carcinoma (n = 4), seminoma (n = 4), fallopian tube ligatures (n = 24), vasectomies (n = 8), nonspecific orchiepididymitis (n = 2), and unknown (n = 8). We have observed ectopic Leydig cells in 13/86 cases (15.11%), 9/72 in the female samples (12.50%) and 4/14 in male samples (28.57%). The most frequent location was the mesosalpinx (4 of 13: 30.76%). These high figures lead us to believe that the ectopia of Leydig cells is not really a pathologic entity, but a finding related to specific functions yet to be determined.
Databáze: OpenAIRE
Externí odkaz: