Figure S4 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression

Autor: Herbert Chen, Brian P. Johnson, Ricardo V. Lloyd, Rebecca S. Sippel, Glen Leverson, Yash R. Somnay, Zviadi Aburjania, Maria R. Georgen, Renata Jaskula-Sztul, Xiao-Min Yu
Rok vydání: 2023
DOI: 10.1158/1078-0432.22457214
Popis: SERPINE1 expression detected by immunohistochemistry in FTC236-Notch1 xenografts with or without Notch1 induction. (A) and (B). Two representative tumors from the group without Notch1 induction (Dox-); (C) and (D). Two representative tumors from the group with Notch1 induction (Dox+). Weaker staining of SERPINE1 (1+) is shown in the Dox+ tumors compared with 3+ staining in Dox- tumors. "Dox" indicates doxycycline; Scale bar: 50µm.
Databáze: OpenAIRE