Practical application of stereological kidney methods in experimental animal models
| Autor: | Juan Argüelles Luis, María del Carmen Muñiz Salgueiro, Aurora Astudillo González, Carmen Méndez, María Teresa Fernández García, Marta Sánchez Pitiot, Paula Núñez Martínez, Vanessa García de la Fuente |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Kidney
Glomerular density 040301 veterinary sciences urogenital system Stereology Experimental Animal Models 04 agricultural and veterinary sciences Nephron Anatomy Biology lcsh:Diseases of the genitourinary system. Urology lcsh:RC870-923 030226 pharmacology & pharmacy 0403 veterinary science Renal stereology 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Nephrology medicine Biological system Glomeruli Relevant information |
| Zdroj: | Nefrología (English Edition), Vol 37, Iss 1, Pp 29-33 (2017) |
| ISSN: | 2013-2514 |
| Popis: | The kidneys are vital organs responsible for excretion, fluid and electrolyte balance and hormone production. The nephrons are the kidney's functional and structural units. The number, size and distribution of the nephron components contain relevant information on renal function. Stereology is a branch of morphometry that applies mathematical principles to obtain three-dimensional information from serial, parallel and equidistant two-dimensional microscopic sections. Because of the complexity of stereological studies and the lack of scientific literature on the subject, the aim of this paper is to clearly explain, through animal models, the basic concepts of stereology and how to calculate the main kidney stereological parameters that can be applied in future experimental studies. |
| Databáze: | OpenAIRE |
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